Biosynthesis of pyocyanin pigment byPseudomonas aeruginosa
نویسندگان
چکیده
منابع مشابه
Biosynthesis, antibacterial activity of pyocyanin pigment produced by Pseudomonas aeruginosa SU1
Pseudomonads are well known for their degradative abilities and play an important role in the environmental cleanup and they are well known for their opportunistic pathogenic properties. The characteristic feature of Pseudomonas aeruginosa is the production of soluble pigments like Pyocyanin, which is an secondary metabolite that is produced in both solid and liquid culture media. Pyocyanin iso...
متن کاملFunctional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.
Two seven-gene phenazine biosynthetic loci were cloned from Pseudomonas aeruginosa PAO1. The operons, designated phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2, are homologous to previously studied phenazine biosynthetic operons from Pseudomonas fluorescens and Pseudomonas aureofaciens. Functional studies of phenazine-nonproducing strains of fluorescent pseudomonads indicated that each of the biosynth...
متن کاملHuman targets of Pseudomonas aeruginosa pyocyanin.
Pseudomonas aeruginosa produces copious amounts of the redoxactive tricyclic compound pyocyanin that kills competing microbes and mammalian cells, especially during cystic fibrosis lung infection. Cross-phylum susceptibility to pyocyanin suggests the existence of evolutionarily conserved physiological targets. We screened a Saccharomyces cerevisiae deletion library to identify presumptive pyocy...
متن کاملStandardized chemical synthesis of Pseudomonas aeruginosa pyocyanin
Preparation of the toxin pyocyanin from the bacterium Pseudomonas aeruginosa is an exacting procedure. Pyocyanin is expensive to commercially purchase. The sellers do not give out the extraction procedure. Classically, pyocyanin preparation involves complicated multi-step P. aeruginosa culturing and solvent transfer extractions. The chemical synthesis first used (1979) has not been adequately d...
متن کاملEffect of fetal and adult bovine serum on pyocyanin production in Pseudomonas aeruginosa isolated from clinical and soil samples
Objective(s): Pyocyanin is a blue-greenish redox-active pigment, produced by Pseudomonas aeruginosa, with a wide range of biological and biotechnological applications. Pyocyanin biosynthesis is regulated by the quorum-sensing (QS) system in which the expression of QS genes and QS-controlled virulence genes may be affected by serum as a complex medium. In the current study, effects of adult bovi...
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ژورنال
عنوان ژورنال: Journal of Radiation Research and Applied Sciences
سال: 2015
ISSN: 1687-8507
DOI: 10.1016/j.jrras.2014.10.007